I started playing Allston Amps in 2013 and never looked back. They're hand wired tube amps custom made right in Allston Village in Boston, MA. With great full sounding clean tones, a dynamic overdrive channel with a boost function (both footswitchable), and a classic spring reverb, I can do a wide variety of gigs plugged straight into the front of the amp. But if I want to add effects, I make use of the line level FX loop. I usually just put the Eventide Timefactor in the loop and leave it at that, but if the gig calls for more effects I'll use the four cable method with the Fractal FX8, which also manages the channel switching on the amp.
The man himself, Rob Lohr, demos the Allston Dumbalina. This is a Mk1 with Reverb, which he called the "Dumbalina Blues" at the time. The newest version, called the "Dumbalina Mk3," has dual concentric knobs which allow for more control over the eq and reverb level in OD mode, while also allowing for a separate master volume in the "Tone Bypass" boost mode.